治疗白癜风误区 http://baidianfeng.39.net/a_zczz/190329/7007685.html由美国约翰霍普金斯大学医学院、瑞士洛桑大学医学中心、以色列耶路撒冷希伯来大学等7间国际顶级医学机构10位学者共同研究表明，CBD可能可用于治疗自身免疫性心肌炎以及其他自身免疫性疾病。该研究发表在MolecularMedicine(年9月刊)，且被美国国立卫生研究院收录。◆◆◆CannabidiolLimitsTCell-MediatedChronicAutoimmuneMyocarditis:ImplicationstoAutoimmuneDisordersandOrganTransplantation《CBD限制T细胞介导的慢性自身免疫性心肌炎：对自身免疫性疾病和器官移植的影响》发表期刊：MolecularMedicine作者：Wen-ShinLee,KatalinErdelyi,CsabaMatyas,ParthaMukhopadhyay,ZoltanVVarga,LucasLiaudet,Gy?rgyHaskú,Daniela?iháková,RaphaelMechoulam,PalPacher发表时间：年9月AbstractMyocarditisisamajorcauseofheartfailureandsuddencardiacdeathinyoungadultsandadolescents.Manycasesofmyocarditisareassociatedwithautoimmuneprocessesinwhichcardiacmyosinisamajorautoantigen.Conventionalimmunosuppressivetherapiesoftenprovideunsatisfactoryresultsandareassociatedwithadversetoxicitiesduringthetreatmentofautoimmunemyocarditis.Cannabidiol(CBD)isanonpsychoactiveconstituentofmarijuanathatexertsantiinflammatoryeffectsindependentofclassicalcannabinoidreceptors.Recently,80clinicaltrialshaveinvestigatedtheeffectsofCBDinvariousdiseasesfrominflammatoryboweldiseasetograftversushostdisease.CBD-basedformulationsareusedforthemanagementofmultiplesclerosisinnumerouscountries,andCBDalsoreceivedU.S.FoodandDrugAdministrationapprovalforthetreatmentofrefractorychildhoodepilepsyandglioblastomamultiforme.Herein,usingawell-establishedmousemodelofexperimentalautoimmunemyocarditis(EAM)inducedbyimmunizationwithcardiacmyosinemmulsifiedinadjuvantresultinginTcell-mediatedinflammation,cardiomyocytecelldeath,fibrosisandmyocardialdysfunction,westudiedthepotentialbeneficialeffectsofCBD.EAMwascharacterizedbymarkedmyocardialT-cellinfiltration,profoundinflammatoryresponseandfibrosis(measuredbyquantitativereal-timepolymerasechainreaction,histologyandimmunohistochemistryanalyses)ac
